The source of most common chronic condition attributed to high blood pressure or hypertension, which affect about 20%–30% of the adult males and female’s population. The present study is aimed to determine the association, of angiotensin converting enzyme genotype with Iraqis’ hypertensive patients. The study was carried out on 30 Iraqi patients having hypertension and 30 healthy subjects as control. Blood samples were collected from both patients and the healthy subjects, DNA from the patients and control specimens were isolated, Detecting of ACE insertion deletion genotype was done by polymerase chain reaction. The results show association between ACE genotype with hypertension DD genotype was increase in patients than control. The present study reported the relation between angiotensin converting enzyme genotype among Iraqis’ hypertensive patients