Background and Objectives: Pseudomonas aeruginosa is gram negative pathogens consederd as the most challenging pathogen. It is one of the most important causative agents of nosocomial infections and difficult to eradicate due to acquired resistance to many antibiotics. The nosocomial infections by P. aeruginosa is considered a major healthcare problem and appearance resistant to many antibiotic.
Materials and Methods: This studied in 45 clinical isolateswere cultured and identified. The P. aeruginosa test by disk agar diffusion method to profiles Antibiotic susceptibility
Results: The Results of disk sensitivity testing for P. aeruginosa showed 35 (77.7%) of P. aeruginosa isolates were sensitive to Cefotaxime , 7 (15.5%) were resistant and 3 (6.6%) of isolates showed intermediate resistance.
Conclusion: The high frequency of Ambiciline resistance was seen among our P. aeruginosa isolates. Since Piperacillin are considered as the last drugs used for treatment of P. aeruginosa infections, it is crucial to screen imipenem non-susceptible isolates in infection control and optimal therapy