Immunity of Outer Membrane Protein of Campylobacter jejuni in Rabbits.
Abstract :
Two groups of rabbits were used, first group was with outer membrane protein (test group) and second with normal saline (control group). Specific antibodies titer were higher in test group than control group in both local and systemic and the ratio of local to systemic antibodies was (10:1)Phagocytosis was studied by using nitrobluetetrazolium dye reduction (NBT) on test group were (0.82,0.84,0.72) comparison with control was (0.7) in systemic respectively.Cell meiated immunity was evaluated by using (LIF). (LIF) was significant in test group and non significant in control group both local and systemic immunity.
Delayed type hypersensitivity test was used in vivo and was significant in control group than test group with (OMP) antigens.It can conclude that (OMP) of C.jejuni induce immune response humeral and cellular local and systemic.