ABSTRACT
Background
: Periodontitis is a chronic inflammatory disease c
ausesinflammation of the supporting
structures of the teeth and especially the periodon
tal membrane, It is the most frequent cause of toot
h
loss in the population mostly in adult patients. Pe
riodontitis is caused by microorganisms that adhere
to
and grow on the tooth s surfaces, along with an ove
r-aggressive immune response against these
microorganisms
Objective
: To examine the association of some immunologica
l parameters such IgA,
IgG antibodies and CRP among periodontitis patients
with coronary heart diseaseand diabetes.
Results
:The mean age of patients was 42.21±4.89years and f
or healthy controls was 40.29±5.62.
Revealed that the serum concentration of IgG and Ig
A are significantly higher than the control, wherea
s,
levels of CRP are elevated in Periodontitis patie
nts where the positive result appear at percent
(93.3%), negative percent at (6.6%) in compares wi
th control group at (20%), (80%) percentage for
positive and negative result respectively.
Conclusion
:These findings documented that the immune
response plays a serious role in the pathogenesis o
f periodontitis with coronary heart disease and DM.
In addition, raised antibody and CRP levels may exp
lain why CHD amplifies periodontitis. So these
results concluded that the immune response plays a
dynamic role in the pathogenesis of periodontitis
with CHD and DM.
KEYWORDS
:
Chronic Periodontitis, Coronary HeartDisease,DM, CR
P, IgG, IgA

(6) Immunological Parameters among Periodontitis Patients with CoronaryHeart Disease and Diabetes,. Available from: https://www.researchgate.net/publication/309413602_Immunological_Parameters_among_Periodontitis_Patients_with_CoronaryHeart_Disease_and_Diabetes [accessed Nov 21 2017].