Background, The other infections of patient in the hospitals may be occur resulting from high drug
résistance bacteria and causes mortality. The study have been aimed to investigate the antibacterial
activity of aqueous extract Borago officinalis L., Cydonia oblonga., Matricaria chamomilla against most
prevalence pathogenic bacteria. Methods; the aqueous extract Borago officinalis L., Cydonia oblonga.,
Matricaria chamomilla were used to investigate the antibacterial activity pathogenic bacteria by Agar
well diffusion method. Result; the Result showed that the crude of all plants extract have potential
antibacterial activity. Conclusion; Based on the results it can be concluded that plants extract can inhibit
bacterial colonization and adherence to upper respiratory tract infection, and provide production against
different human pathogens and this may have clinical relevance.