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inorganic pharmaceutical chemistry 1

الكلية كلية العلوم للبنات     القسم قسم الكيمياء     المرحلة 3
أستاذ المادة محمد حامد سعيد الدهيمي       12/11/2016 09:53:16

inorganic pharmaceutical chemistry 1

Reference text:-
1- Inorganic Medicinal and Pharmaceutical Chemistry
by Block ,Roche Soine and Wilson
2- Textbook of Organic Medicinal and pharmaceutical Chemistry by Wilson and Gisvold
Course Coverage
Atomic and Molecular Structure
1-Structure of the Atom
2-Atomic Number, Mass Number, & Isotopes
3-Classification of the Elements
4- Quantum Mechanics, Quantum Numbers
5- Electronic Configuration
6-Shielding
7-Atomic Radius, Ionic Radius, Ionization Energy, Electron Affinity, Electronegativity
8-Chemical bond
Complexes
1- Orbital hybridization
2-Types of hybridization
3- Basic theory
- Valence bond theory
4- Rules for Naming Coordination Complexes
5- Ligand
Atomic Structure
Structure of the Atom
Composed of:
1- Nucleus
protons
Neutrons
2- Orbitals
electrons
protons
found in nucleus
relative charge of +1 , relative mass of 1.0073 amu
neutrons
found in nucleus
neutral charge , relative mass of 1.0087 amu
electrons
found in electron cloud
relative charge of -1 , relative mass of 0.00055 amu
Protons are positively charged and so would be deflected on a curving path towards the negative plate.
Electrons are negatively charged and so would be deflected on a curving path towards the positive plate.
Neutrons don t have a charge, and so would continue on in a straight line.
If beams of the three sorts of particles, all with the same speed, are passed between two electrically charged plates:
The nucleus
The nucleus is at the centre of the atom and contains the protons and neutrons. Protons and neutrons are collectively known as nucleons.
Virtually all the mass of the atom is concentrated in the nucleus, because the electrons weigh so little.
Working out the numbers of protons and neutrons
No of protons = ATOMIC NUMBER of the atom
The atomic number is also given the more descriptive name of proton number.
No of protons + no of neutrons = MASS NUMBER of the atom


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