mucosal component

mucosa – associated lymphoid tissue or (MALT)mponent
Dr. Baha. Hamdi. Al-amiedi
Local immune component are recently being talked by immunologist as an active local immune system it consist of both B- and T- Cells epithelial cell producing secretory piece they can fix up both humoral and cellular immune response in site , the mucosa – associated lymphoid tissue or (MALT) the main mucosa- associated lymphoid tissue are the gastrointestinal tract ( inclsalivery gland , the genitourinary tract , the respiratory tract and the secretion of the mammary glands
this local immune stimulated through mucosa- associated lymphoid tissue which is organized into discrete areas in the gut known as Peyer patches just below the epithelial cells in the lamina propria Antigen travels through specialized epithelium(M Cells) to the subepithelial lymphoid tissue. The main antibody produced at these sites is secretory IgA , dimeric immunoglobulin which aquires it secretory component during transport across the epithelium
uding oral mucosa and salivery gland , the genitourinary tract , the respiratory tract and
mmunity of oral cavity : the oral cavity environment is controlled primary by saliva mucosal surface saliva contain several non-specific host factores (mucins,lactoferrin,lysozyme, peroxidase, Histatins, cystains, salivery glycoprotein)
It is well established that S.IgA is predominant immunoglobulin in whole saliva it is considered to be the main specific defense mechanism in oral surface by limiting
microbial adherence to epithelial & tooth surface by neutralizing toxin& host factors another part of oral cavity immunty