Mucosal component

Mucosal component
Dr.Baha.Hamdi. AI-Amiedie
Ph.D.Microbiology
local immune component are recently being talked by immunologist as an active local immune system it consist of both B- and T- Cells epithelial cell producing secretory piece they can fix up both humoral and cellular immune response in site , the mucosa – associated lymphoid tissue or (MALT) the main mucosa- associated lymphoid tissue are the gastrointestinal tract ( including oral mucosa and salivery gland , the genitourinary tract , the respiratory tract and the secretion of mammary gland
this local immune stimulated through mucosa- associated lymphoid tissue which is organized into discrete areas in the gut known as Peyer patches just below the epithelial cells in the lamina propria Antigen travels through specialized epithelium(M Cells) to the subepithelial lymphoid tissue. The main antibody produced at these sites is secretory IgA , dimeric immunoglobulin which aquires it secretory component during transport across the epithelium
immunity of oral cavity
immunity of oral cavity : the oral cavity environment is controlled primary by saliva mucosal surface saliva contain several non-specific host factores (mucins,lactoferrin,lysozyme, peroxidase, Histatins, cystains, salivery glycoprotein)