انت هنا الان : شبكة جامعة بابل > موقع الكلية > نظام التعليم الالكتروني > مشاهدة المحاضرة
الكلية كلية طب الاسنان
القسم العلوم الاساسية
المرحلة 3
أستاذ المادة علي زكي ناجي الاسدي
5/31/2011 6:51:48 AM
Chronic inflammation:
It is a slowly progressing inflammatory process that persists for weeks, months or years after initial injury.
Differences from acute infection.
1- Chronic inflammation associated with more tissue destruction.
2- The main inflammatory cells are lymphocytes, plasma cells and macrophages.
3- It associated with granulation tissue formation and fibrosis rather than exudates fluid formation.
Causes of chronic inflammation:
1- Progressive from acute inflammation, like chronic abscess due to inadequate drainage of the pus, as in abscess of the bone, or associated with inflammation induced by foreign material like surgical suture, implant, piece of wood, ...
2- Recurrent episodes of acute inflammation and best example for this is chronic cholecystitis induced by repeated acute cholecystitis that associated with gall stones, and also in case of osteomyelitis.
3- Primary chronic inflammation (ab initio): This type of inflammation do not preceded by acute inflammation and this inflammation seen in the follow conditions:
a- Exposure to potentially toxic, non-degradable substances like Silica, and Asbestoses.
b- Exposure to certain infectious agents like (T.B., Leprosy, and fungal infections).
c- In certain diseases that result from immune system abnormality, like rheumatoid arthritis and Crohn s disease. Macroscopical appearance of chronic inflammation:
A- Chronic ulcer like chronic peptic ulcer of the stomach.
B- Chronic abscess like in osteomyelitis.
C- Thickening of the wall of hallow viscus by fibrosis like in chronic cholecystitis.
D- Granulomatous inflammation. Granulomatous inflammation: It is a distinctive pattern of inflammation characterized by aggregation of activated and modified macrophages called epitheliod cells exhibit vesicular nuclei, and eosinophillic cytoplasm that arranged in small clusters or nodular collection cuffed by rim of lymphocytes, and some times fibroblasts, this aggregate called granuloma. In T.B. granuloma there is caseous necrosis formation characterized by soft, whitish, cheese-like material, the T.B. granuloma also characterized by formation of Langhan s giant cell that arise by fusion of many macrophages, in which their nuclei arranged at the periphery of the giant cell giving characteristic horse shoe appearance.
Causes of granulomatous inflammation:
1- T.B., 2- Syphilis, 3- Leprosy, 4- fungal infection, 5- Sarcoidosis, and 6 reaction to foreign bodies like suture, or any indigestible substances .
المادة المعروضة اعلاه هي مدخل الى المحاضرة المرفوعة بواسطة استاذ(ة) المادة . وقد تبدو لك غير متكاملة . حيث يضع استاذ المادة في بعض الاحيان فقط الجزء الاول من المحاضرة من اجل الاطلاع على ما ستقوم بتحميله لاحقا . في نظام التعليم الالكتروني نوفر هذه الخدمة لكي نبقيك على اطلاع حول محتوى الملف الذي ستقوم بتحميله .
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