Introduction for this course

In this lecture I will explain the syllabus that we will study in this course In Shaa Allaah:

Title of the course: Physical Pharmacy I.
Course number: 213
Title of the course: Physical Pharmacy I Course number: 213
Level: 2nd Class, 1st Semester
Credit hours/week : Theory 3 Laboratory 1
Reference text:
1-Martin,s Physical Pharmacy and Pharmaceutical Sciences, 50th Edition, 2011.
2- Principles of Thermodynamics, Falah H. Hussein Edition 2, 2012.
Objectives of the course: To understand the application of quantitative and theoretical principles of the physical characters of matter in the practice of pharmacy. It aids the pharmacists in their attempt to predict the solubility, compatibility and biological activity of drug products. As a result of this knowledge it will help in the development of new drugs and dosage forms as well as in improvement of various modes of administration.

No. Lecture title No. of Hours
1 States of matter, binding forces between molecules, gases, liquids, solid and crystalline matters; phase equilibria and phase rule; thermal analysis. 10
2 Thermodynamics, first law, thermochemistry, second law, third law,
free energy function and applications. 8
3 Solutions of non-electrolytes, properties, ideal and real colligative
properties, molecular weight determination. 7
4 Solution of electrolytes, properties, Arrhenius theory of dissociation,
theory of strong electrolytes, ionic strength, Debye-Huchle theory, coefficients for expressing colligative properties. 5
5 Ionic equilibria, modern theories of acids, bases and salts, acid-base
equilibria, calculation of pH, acidity constants, the effect of ionic strength and free energy. 8
6 Buffered and isotonic solutions: Buffer equation; buffer capacity;
methods of adjusting tonicity and pH; buffer and biological system. 7
7 Mid Examination 2