protein metabolism

METABOLISM
OF
AMINO ACIDS
assistant professor Dr.
Abdulhussien M. Aljebory
College of pharmacy
Babylon University
1.Introduction
2.Amino acid classification
3.Some definitions:
- nitrogen balance (NB)
- protein requirement
- biological value (BV)
4.Digestion of protein
5.Absorption of protein
6.Metabolic fate of protein
7.Metabolism of amino acids:
- removal of ammonia: by deamination, transamination and transdeamination
- fate of carbon skeletons of amino acid
- metabolism of ammonia
Protein Metabolism
•Non-essential amino acids can be formed by transamination, transfer of an amine group to keto acid. Can also be eaten.
•If used for energy, amino acids undergo oxidative deamination. Ammonia and keto acids are produced as by-products of oxidative deamination. Ammonia is converted to urea and excreted.
•Amino acids are not stored in the body
*Metabolism of proteins is the metabolism
of amino acids. NH2 COOH
*Metabolism of amino acids is a part of the
nitrogen metabolism in body.
*Nitrogen enters the body in dietary protein.
*Dietary proteins cannot be stored as such but
used for formation of tissue proteins due to
there is a continuous breakdown of
endogenous tissue proteins.