hypersensitivity type I

Immune system disorders
*Learning objectives:-
1- Classify disorders of the immune system.
2-Identify mechanisms of hypersensitivity reactions.
3-Define (immediate hypersensitivity, allergy, allergen.)
4-Identify types of immediate hypersensitivity.
5- Describe the two phases of local reaction of type I hypersensitivity.
6-Discuss the role of mast cell in type I hypersen.
7-Discuss the role of basophil in type I hypersen.
8-Explain the mechanism of immediate hypersen.
9-List the categories of mediators in type I hypersen.
10-Discuss the types,formation,sources, & actions of mediators of type I hype.
Immediate hypersensitivity
-Definition of:
*Type I hypersensitivity.
*Allergy.
*Allergen.
*Atopic allergy.
*Systemic anaphylaxis.
Introduction to hypersensitivity reaction
*Human-------Environment-------Ag.
*Types of Ags.
*Types of hypersensitivity reactions

*Questions :-

1-Mention the role of the following cells in pathogeneses in type 1 hypersensitivity :-
a-macrophage
b-mast cell, basophil and esinophil
2-Enumerate the primary and secondary mediaters in type 1 hypersensitivity and give thier sources and actions ?



References:
___________
1-MacSween R.N.;and Whaly K.(Murs Textbook of pathology); 13th edition,Arlond.1997.
2-Kumar V.;Abbas A.; and Fausto N.(Robbin and Cortan, Pathologic basis of disease).7th edition. Elsevier Sounder. 2004.
3-Rosal J. (Ackerman s surgical pathology); 9th edition.Mosby.2003.