Rabies-CDCreport

Rabies

ICD-10 A82

1.10.1 Identification

A fatal acute viral disease caused by rabies virus, a rhabdovirus of the genus Lyssavirus, whose first symptoms may be apprehension, headache and indefinite sensory changes, fever, malaise, water and air phobia, and paralysis. It is transmitted in the saliva of infected animals, most commonly through bites. Rabies is an acute encephalomyelitis that almost progresses to coma or death within 10 days after the first symptoms.
Rabies

ICD-10 A82

1.10.1 Identification

A fatal acute viral disease caused by rabies virus, a rhabdovirus of the genus Lyssavirus, whose first symptoms may be apprehension, headache and indefinite sensory changes, fever, malaise, water and air phobia, and paralysis. It is transmitted in the saliva of infected animals, most commonly through bites. Rabies is an acute encephalomyelitis that almost progresses to coma or death within 10 days after the first symptoms.Case classification
Suspected: A case that is compatible with the clinical description.
Probable: Not applicable.
Confirmed: A suspected case by especial laboratory investigation

Laboratory criteria for diagnosis
One of the following:
• Detection of rabies viral antigens by direct florescent antibody (FA) in clinical specimens, preferably brain tissue (collected post mortem).
• Detection by FA on skin or corneal smear (collected ante mortem).
• FA positive after inoculation of brain tissue, saliva or CSF in cell culture, in mice or in sucking mice