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Function of The Stomach

الكلية كلية طب حمورابي     القسم الكلية ذات القسم الواحد     المرحلة 2
أستاذ المادة امجد حسن عباس المنصوري       10/03/2019 16:47:46
Objectives ? describe the functions of the stomach ? describe the components of gastric secretion and their cellular origins ? explain the mechanism of secretion of stomach acid ? explain the control of gastric acid secretion ? outline the ways in which gastric acid secretion may be reduced by drugs describe the function of the stomach defences ? describe the patterns of motility of the stomach, including receptive relaxation and peristalsis ? describe the process of gastric emptying and its control
The functions of the stomach
o Stores Food
o Disinfects Food
o Breaks food down into Chyme
o Chemical disruption (Acid and enzymes)
o Physical disruption (Motility)
Stomach secretions come from Gastric Pits, indentations in the stomach mucosa that are the openings to gastric glands.
Gastric pits contain Neck Cells, and gastric glands contain Parietal, Chief and G-Cells, along with smooth muscle cells.
A complex of neural and endocrine systems controls acid secretion. Parietal cells are stimulated by Acetylcholine, Gastrin and Histamine, which act via separate receptors to promote acid secretion.
Acetylcholine Ach is released from postganglionic parasympathetic neurones, stimulated by gastric distension as food arrives. It acts on muscarinic receptors on parietal cells.
Gastrin Gastrin is released from endocrine cells in the stomach, G-Cells. It is a 17amino acid polypeptide, which binds to surface receptors on parietal cells. Gastrin secretion is stimulated by the presence of peptides and Ach from intrinsic neurones. It is inhibited by low pH in the stomach, which acts as a feedback control.

المادة المعروضة اعلاه هي مدخل الى المحاضرة المرفوعة بواسطة استاذ(ة) المادة . وقد تبدو لك غير متكاملة . حيث يضع استاذ المادة في بعض الاحيان فقط الجزء الاول من المحاضرة من اجل الاطلاع على ما ستقوم بتحميله لاحقا . في نظام التعليم الالكتروني نوفر هذه الخدمة لكي نبقيك على اطلاع حول محتوى الملف الذي ستقوم بتحميله .